

Rock inhibitor
Nuwacell® Blebbistatin(RP01008)is a widely used non-muscle myosin type II ATPase inhibitor. Blebbistatin acts on the ROCK-myosinII signaling pathway, which can prevent the apoptosis of pluripotent stem cells due to digestion, thus improve the cell survival rate; and also can maintain the self-renewal or pluripotency characteristics of hPSCs.
Contents | Amount | Cat. No. | Storage |
Nuwacell® Blebbistatin |
3mg(1mL) | RP01008 | -20℃ |

The morphorlogy of hPSC cultured at day 1, 2, and 3 after passaging (P18) in ncEpic with Blebbistatin (2.5 μM). Scale bar, 200 μm.

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Transplantation of GMP-grade human iPSC-derived retinal pigment epithelialcells in rodent model- the first pre-clinical study for safety and efficacy in ChinaHang Zhang,et al.Ann Transl Med 2021(IF 3.616).
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Establishment of an induced pluripotent stem cell line from a patient with hereditary transthyretin amyloidosis carrying transthyretin (TTR) mutation p.Phe53Val2020. He Shan, et al. Stem Cell Research(IF 1.587).
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Establishment of an induced pluripotent stem cell line PUMCHi004-A from a hereditary transthyretin amyloid cardiomyopathy patient with transthyretin (TTR) p.Asp38Asn mutation2020. He Shan , et al. Stem Cell Research(IF 1.587).
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