Rock inhibitor

Rock inhibitor

Nuwacell^® Blebbistatin（RP01008）is a widely used non-muscle myosin type II ATPase inhibitor. Blebbistatin acts on the ROCK-myosinII signaling pathway, which can prevent the apoptosis of pluripotent stem cells due to digestion, thus improve the cell survival rate; and also can maintain the self-renewal or pluripotency characteristics of hPSCs.

  Product manual download

Contents	Amount	Cat. No.	Storage
Nuwacell® Blebbistatin	3mg(1mL)	RP01008	-20℃

1、Cell morphology

 

The morphorlogy of hPSC cultured at day 1, 2, and 3 after passaging (P18) in ncEpic with Blebbistatin (2.5 μM). Scale bar, 200 μm.

Citations & References

• Transplantation of GMP-grade human iPSC-derived retinal pigment epithelialcells in rodent model- the first pre-clinical study for safety and efficacy in China

  Hang Zhang,et al.Ann Transl Med 2021(IF 3.616).
• Establishment of an induced pluripotent stem cell line from a patient with hereditary transthyretin amyloidosis carrying transthyretin (TTR) mutation p.Phe53Val

  2020. He Shan, et al. Stem Cell Research(IF 1.587).
• Establishment of an induced pluripotent stem cell line PUMCHi004-A from a hereditary transthyretin amyloid cardiomyopathy patient with transthyretin (TTR) p.Asp38Asn mutation

  2020. He Shan , et al. Stem Cell Research(IF 1.587).

View all references

Please call 400 888 3920 for more references.